Here are the 55 US AI startups that raised $100M or more in 2025

The AI industry entered 2025 with strong momentum.

There were 49 startups that raised funding rounds worth $100 million or more in 2024, per our count at TechCrunch; three companies raised more than one “mega-round,” and seven companies raised rounds that were $1 billion in size or larger.

The industry didn’t slow down in 2025. While less companies raised rounds larger than $1 billion, four — Anthropic raised two rounds over $1 billion — significantly more companies raised multiple rounds compared to 2024, eight.

How will 2026 compare? Elon Musk’s xAI announced a $20 billion Series E round and Sam Altman’s brain computer interface startup Merge Labs raised a $250 million seed round (with OpenAI as the lead investor) in the first few weeks of 2026, so signs point to another strong year. Of course, it’s still early; we’ll be watching to see if the momentum continues.

Here are all the U.S. AI companies that raised $100 million last year:

This piece was updated on April 23, June 18, August 27, November 26 and January 19, 2026 to include more deals.

This piece has been updated to remove that Abridge is based in Pittsburgh; the company was founded there.

When you purchase through links in our articles, we may earn a small commission. This doesn’t affect our editorial independence.

Scale faster. Grow your portfolio. Gain practical expertise. No matter your goal, Disrupt can empower you.Save up to $330 today!

Librarians are hosting viral ‘Avoiding AI’ workshops for people who are fed up with Big Tech

SpaceX launches new V3 Starlink satellites but suffers another booster failure

Prentis, new AI lab co-founded by Reid Hoffman, Mark Pincus in talks to raise $100M

US accuses American of allegedly wiping his phone using a ‘duress’ password during border search

Anduril reportedly in talks to raise funding at $100B valuation, more than 3x last year’s mark

OpenAI makes ChatGPT Health available to all US users